Secreted Wnt proteins regulate development and adult tissue homeostasis by binding and activating cell-surface Frizzled receptors and co-receptors including LRP5/6.The hydrophobicity of Wnt proteins has complicated their purification and limited their use in basic research and as therapeutics.We describe modular tetravalent antibodies that can recr
In this study, we investigated the correlation between fracture classification and secondary screw penetration.We retrospectively identified 189 patients with displaced proximal humeral fractures treated by ORIF at our hospital between June 2006 and June 2013.All fractures were classified radiographically before surgery and follow-up for least 2 ye
Motivation for the studyWorkplaces are changing with employees increasingly working remotely and flexibly, which has created larger physical distance between team members.This shift has consequences for trust research and implications for how trust is built and maintained between employees and leaders.Research designThree studies collectively aimed